Regenerative medicine Historical roots and potential strategies in modern medicine》.pdf

Journal of Microscopy and Ultrastructure 3 (2015) 101–107 Contents lists available at ScienceDirect Journal of Microscopy and Ultrastructure j o u r n a l h o m ep a g e: w w w. els e v i e r. co m/loc ate /jmau Review article Regenerative medicine: Historical roots and potential strategies in modern medicine Gianluca Sampogna a , Salman Yousuf Guraya b , Antonello Forgione a,∗ a Advanced International Mini-invasive Surgery – AIMS Academy, Milan, Italy b Department of Surgery, Taibah University, Madinah, Saudi Arabia a r t i c l e i n f o a b s t r a c t Article history: Regenerative medicine is a distinct major advancement in medical treatment which is based Received 19 December 2014 on the principles of stem cell technology and tissue engineering in order to replace or Received in revised form 4 May 2015 regenerate human tissues and organs and restore their functions. After many years of basic Accepted 8 May 2015 research, this approach is beginning to represent a valuable treatment option for acute Available online 18 May 2015 injuries, chronic diseases and congenital malformations. Nevertheless, it is a little known field of research. The purpose of this review is to convey the state of the art in regenerative Keywords: medicine in terms of historical steps, used strategies and pressing problems to solve in the