微波促进条件下炔烃参和的氢胺化加成及其偶联反应的研究.pdf

摘要 本文在调研大量文献的基础上，综述了炔烃的氢胺化灰应寻贡蘑阿百1禹联反 一…一㈣上，篡…胺化一 关键词：微波，E型烯胺，自偶联，丙炔酸酯 Abstract Inthis alotofliteraturesonthebasisof paper,wesurveyed alkynes reactionand wellasthe of hydroaminationcouplingreaction,as synthesis propiolic acid forwardthe ofthisthesis． ester,andput designthought 1． In this reactionof paper,alkyneshydroamination Dimethyl acetylenediearboxylate，Ethylpropiolate,Methyl were intheconditionofmicrowave E-enamine of were put irradiation,theproducts obtainedinthe influence the ofdifferent and highselectivity,andstudyed alkynes various to of substitutedaminesthe additionreaction． activityalkynehydroaminafion Andwefoundthatthesame obtainedbetween product Dimethyl withDMF acetylenedicarboxylatereacting whichWastreatedwithsodiumandnot donewith the twokindsof sodium,throughdesigningexperiment,weproposed mechanism ofreactionbetween andDMF． Dimethylacetylenedicarboxylate 2．Inthis foundthat and paper,we Phenylacetylene could and the of generateconjugatedefficientlyhighlyyield