《The recurrence and survival of oral squamous cell carcinomaa report of 275 cases》.pdfVIP

Chinese Journal of Cancer Original article The recurrence and survival of oral squamous cell carcinoma: a report of 275 cases - Bo Wang, Shu Zhang, Kai Yue and Xu Dong Wang Abstract Oral squamous cell carcinoma (OSCC) is a common malignant tumor of the head and neck, and recurrence is an important prognostic factor in patients with OSCC. We explored the factors associated with recurrence of OSCC and analyzed the survival of patients after recurrence. Clinicopathologic and - follow up data of 275 patients with OSCC treated by surgery in the Cancer Institute and Hospital of Tianjin Medical University between 2002 and 2006 were analyzed. Recurrence factors were analyzed with Chi- square or Fisher′s exact test and multivariate analysis. The prognosis of patients after recurrence was - - analyzed with the Kaplan Meier method and log rank test. The recurrence rate was 32.7%. The recurrence time ranged from 2 to 96 months, with a median of 14 months. Univariate analysis showed that T stage, degree of differentiation, pN stage, flap application, resection margin, and lymphovascular invasion were factors of recurrence (P 0.05). Multivariate analysis showed that T stage, degree of differentiation, and pN stage were independent factors of recurrence (P 0.001). The differences in gender, age, tumor site, -