《Effect of hyperbaric oxygen preconditioning on the expression of aquaporin 5 in rats with high-altitude pulmonary edema》.pdfVIP
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《Effect of hyperbaric oxygen preconditioning on the expression of aquaporin 5 in rats with high-altitude pulmonary edema》.pdf
·257·
.高原环境下高压氧研究.
Effectofhyperbaricoxygen
。。 ● ●● ■ 一 ● ‘ 一
0nthe 0I 5inrats
eXpreSSlonaquaporln with
high·-altitude edema
pulmonary
ZHAO
L/Zhuo, Li‘ming,WANGCong,LIUXue—hua,GAO
Chun-fin.Departmentof
Hyperbaric Medical
Oxygen,BeoingChaoyangHospital,Capital 100020,
University,Beijing
China
author:GAO
CorrespondingChun-jin,E—mail:gchjw@hotmail。corn
To the of
【Abstract】objective
investigatepossibility
applyinghyperbaricoxygen
reduceor
preconditioning(HBO—PC)toprevent edema(HAPE)and
high—altitudepulmonary
to whether
detect involvedinHAPE
aquaporin5(AQP5)are pathogenesis.MethodsThirty
were
rats dividedintothree HBO.PCandtheHAPE
contr01.the
eight groups:the groups.
Westernblotand
real—timePCRwereusedto the of inthe
analyzeexpressionAQP5 lungs.The
ofthe werealso
wet—to—dry ratio(W/Dratio)and examined.
weight weight morphologylung
Results W/D ratiointheHAPE withthat
ofthe
Lung weight group(4.36±0.53)compared
control markedinterstitialedemainallthe sections
group(3.90±0.15)(P0.05),were lu
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