《ADA关于HbA1c诊断糖尿病的专家共识》.pdf

R e v i e w s / C o m m e n t a r i e s / A D A S t a t e m e n t s A D A W O R K G R O U P R E P O R T International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes THE INTERNATIONAL EXPERT COMMITTEE* criteria that would serve as the blueprint for nearly two decades (12). The NDDG relied on distributions of glucose levels, An International Expert Committee with most clinical settings. On the other hand, rather than on the relationship of glucose members appointed by the American Diabe- type 2 diabetes has a more gradual onset, levels with complications, to diagnose di- tes Association, the European Association for with slowly rising glucose levels over abetes despite emerging evidence that the the Study of Diabetes, and the International time, and its diagnosis has required spec- microvascular complications of diabetes Diabetes Federation was convened in 2008 to ified glucose values to distinguish patho- were associated with a higher range of consider the current and future means of di- logic glucose concentrations from the fasting and OGTT glucose values (11,13– agnosing diabetes in nonpregnant individu- distribution of glucose concentrations in 15). The diagnostic glucose values chosen als. The report of the International Expert the nondiabetic population. Virtually ev- were based on their association with de- Committee represents the consensus view of ery scheme for the classification and diag- compensation to “overt” or symptomat