三种脱敏牙膏对牙本质小管封闭作用的扫描电镜观察李锐,周智,陈娇,李月恒(重庆医科大学口腔医学院,重庆400015).docVIP

三种脱敏牙膏对牙本质小管封闭作用的扫描电镜观察李锐,周智,陈娇,李月恒(重庆医科大学口腔医学院,重庆400015).doc

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三种脱敏牙膏对牙本质小管封闭作用的扫描电镜观察李锐,周智,陈娇,李月恒(重庆医科大学口腔医学院,重庆400015).doc

三种脱敏牙膏对牙本质小管封闭作用的扫描电镜观察 李锐,周智*,陈娇,李月恒 (重庆医科大学 口腔医学院,重庆 400015) 摘要 目的:评价3种脱敏膏(高露洁专效抗敏牙膏,舒适达原味牙膏,GC 牙膏)对牙本质小管的封闭堵塞能力,为治疗牙本质敏感症提供参考。方法:新鲜拔出的完整无龋的第三磨牙制备40个牙本质小块,随机分为4组(n=10),G1:阴性对照组;G2:GC牙膏刷牙组;G3:舒适达牙膏刷牙组;G4:高露洁牙膏刷牙组。牙膏处理组各牙本质小块分别采用同一规格牙刷蘸取等量膏浆早晚刷牙200下,其余时间浸泡于除菌人唾液中,对照组直接置于人唾液中,持续10天。处理后样本置于扫描电镜下观察牙本质小管的封闭效果,采用图像分析软件量化牙本质小管的封闭程度。结果运用方差分析和Tukey,s检验分析统计。结果: 3种牙膏对牙本质小管都有一定封闭作用,但每种膏浆的封闭能力有较大差异。结论:结果表明3种脱敏牙膏有封闭牙本质小管的能力,而高露洁专效抗过敏牙膏对牙本质小管的封闭效果最佳。 关键词:牙本质敏感症,脱敏牙膏,牙本质小管封闭 The sealing effects of three desensitizing toothpastes on tubules: an SEM investigation LI Rui,Zhou Zhi*, Chen JiaoCollege of Stomatology, Chongqing Medical University, Chongqing 400015, China Abstract Objectives: To evaluate the sealing effect of three desensitizing toothpastes on dentine tubules in vitro. Methods: 40 dentin discs were obtained from healthy third molars and randomly divided into 4 groups (n=10), which were negative control group, Colgate toothpaste, Sensodyne toothpastes and GC Tooth Mousse group, The dentifrices were undiluted and topically applied to dentine surface for brushing 200 strokes, twice a day, and then soaked in degermed human saliva. The negative control group was brushed without any toothpaste, then directly soaked in degermed human saliva. The treatment processes were repeated 10 days. The sealing effect of the dentin tubules was observed using scanning electron microscopy (SEM). The degree of occlusion of the dentinal tubules was quantified using an image analyser and the results were analyzed by ANOVA and a Turkey’s test .Results: SEM observations revealed that the sealing of dentinal tubules of Colgate toothpaste which containing arginine was extremely high when compared with those of control and Sensodyne toothpastes and GC Tooth Mousse group. Conclusion: the application of the Colgate toothpaste containing arginine and calcium carbonate could occlude dentinal tubules more effectively in vitro. Keywords:dentin hypersensitivity,desensitizing dentifrice,dentinal tubule occlu

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