组织多普勒成像技术评价尿毒症患者左,右心室功能王凤双,孙志丹2(辽宁医学院附属第一医院超声科,辽宁锦州121001).docVIP

组织多普勒成像技术评价尿毒症患者左、右心室功能 王凤双，孙志丹 （辽宁医学院附属第一医院超声科，辽宁锦州121001） Tissue Doppler Imaging in evaluating the function of left and right ventricles in patients with uremia Wang Fengshuang1, Sun Zhidan2 (Department of Ultrasound, the First Hospital Affiliated to Liaoning Medical University, Jinzhou121001, China) [Abstract] Objective: To explore the value of tissue doppler imaging(TDI) in the evaluation of diastolic and systolic ventricular function in both left and right ventricles in patients with uremia. Methods: 40 patients with uremia and 40 normal subjects were studied with Tissue Doppler Imaging. Results: Compared with normal subjects, left and right ventriculars diastolic function of patients with uremia were that ratio of E and A is less than one, the ratio of Em and Am is less than one, too(P0.05). Sm as an indicator of left and right ventriculars systolic function was a statistically significant difference between patients with uremia and normal subjects(P0.05)Patients with uremia had left and right ventriculars diastolic and systolic dysfunction. Conclusion: Patients with uremia had left and right ventriculars diastolic dysfunction,and so were systolic function.These alterations in myocardial function may be attribute to ventricular interdependence as well as to the uniform effect of uremia to cardiac function. [Key words] tissue doppler imaging; uremia; ventricular function [摘要]目的 探讨组织多普勒成像技术评价尿毒症患者左、右心室的收缩和舒张功能的价值。方法 通过组织多普勒成像技术对40例尿毒症患者和40例正常受试者左、右心室的收缩和舒张功能进行研究。结果 尿毒症组右心室与正常对照组相比E/A1Em/Am1（P 0.05,）；右心室收缩功能指标Sm与正常对照组相比（P0.05）结论 尿毒症患者存在左、右心室舒张功能障碍，收缩功能亦受损，这些功能的改变与心室的相互依赖和尿毒症对心脏功能的等同作用有关。 [关键词] 组织多普勒成像技术；尿毒症；心室功能[中图分类号] R540.45 [文献标识码] A 心是尿毒症患者的并发症，也是透析患者的首位死亡原因，约50%的尿毒症患者死于心血管并发症[1]。 以往的文献中，我们看到较多应用组织多普勒技术（Tissue Doppler Imaging, TDI）对尿毒症患者左心室功能报道，而对右心室功能变化的探讨不多本研究用TDI尿毒症患者右心室的收缩和舒张功能临床治疗指导。 1 资料与方法 1.1 研究对象 尿毒症组：选择2009年9月~2010年7月在我院住院或经门诊确诊的尿毒症患者40例，其中男20例，女20例，年龄37 ~ 70岁，平均（54±11）岁。入选标准：所有患者原发病均为肾病，其中肾小球肾炎20例；肾盂肾炎12例；多囊肾8例；患者的心率均为窦性心律，左室射血分数大于50%，无局限性收缩功