Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes A Prespecified Analysis of the Benedict Trial.pdfVIP

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Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes A Prespecified Analysis of the Benedict Trial.pdf

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Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes A Prespecified Analysis of the Benedict Trial.pdf

Hindawi Publishing Corporation Journal of Ophthalmology Volume 2010, Article ID 106384, 9 pages doi:10.1155/2010/106384 Clinical Study Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes: A Prespeciﬁed Analysis of the Benedict Trial Piero Ruggenenti,1, 2 Ilian Iliev,1 Marco Filipponi,3 Stefano Tadini,3 Annalisa Perna,1 Maria Ganeva,1 Bogdan Ene-Iordache,1 Paolo Cravedi,1 Roberto Trevisan,4 Antonio Bossi,5 and Giuseppe Remuzzi1, 2 1 Clinical Research Center for Rare Diseases ‘Aldo Cele Dacco’, Mario Negri Institute for Pharmacological Research, ` Negri Bergamo Laboratories, Via Gavazzeni, 11, 24125 Bergamo, Italy 2 Unita di Nefrologia, Azienda Ospedaliera Ospedali Riuniti di Bergamo, 24128 Bergamo, Italy ` 3 Unita di Oftalmologia, Azienda Ospedaliera Ospedali Riuniti di Bergamo, 24128 Bergamo, Italy ` 4 Unita di Diabetologia, Azienda Ospedaliera Ospedali Riuniti di Bergamo, 24128 Bergamo, Italy ` 5 Unita di Diabetologia, Treviglio Hospital, 24047 Bergamo, Italy ` Correspondence should be addressed to Piero Ruggenenti, pruggenenti@ospedaliriuniti.bergamo.it Received 19 November 2009; Revised 21 January 2010; Accepted 11 March 2010 Academic Editor: Renu A. Kowluru Copyright © 2010 Piero Ruggenenti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. The eﬀect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill d