Elimination of the Actin-Binding Domain in Kelch-Like 1 Protein Induces T-Type Calcium Channel Modulation Only in the Presence of Action Potential Waveforms.pdfVIP

Hindawi Publishing Corporation Journal of Signal Transduction Volume 2012, Article ID 505346, 8 pages doi:10.1155/2012/505346 Research Article Elimination of the Actin-Binding Domain in Kelch-Like 1 Protein Induces T-Type Calcium Channel Modulation Only in the Presence of Action Potential Waveforms Kelly A. Aromolaran,1, 2 Kelly A. Benzow,3 Leanne L. Cribbs,4 3 ´ 5, 6 Michael D. Koob, and Erika S. Piedras-Renterıa 1 Neuroscience Graduate Program, Loyola University Chicago, Chicago, IL 60153, USA 2 Department of Neuroscience, Kennedy Center, Albert Einstein College of Medicine, Room 610, 1300 Morris Park Avenue, NY 10461, USA 3 Institute of Human Genetics, University of Minnesota, MMC 206, 420 Delaware Street SE, Minneapolis, MN 55455, USA 4 Offi ce of Research Services, Room 4601, Building 102, 2160 S. First Avenue, Maywood, IL 60153, USA 5 Cellular and Molecular Physiology Department, Stritch School of Medicine, Loyola University Chicago, Room 4669, Building 102, 2160 S. First Avenue, Maywood, IL 60153, USA 6 Neuroscience Institute, Stritch School of Medicine, Loyola University Chicago, Room 4669, Building 102, 2160 S. First Avenue, Maywood, IL 60153, USA ´ Correspondence should be addressed to Erika S. Piedras-Renterıa, erikapiedras@ Received 6 April 2012; Accepted 30 May 2012 Academic Editor: Jesus Garcia Copyright © 2012 Kelly A. Aromolaran et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Kel