Genetic Variations of Glutathione S-Transferase Influence on Blood Cadmium Concentration.pdfVIP

Hindawi Publishing Corporation Journal of Toxicology Volume 2012, Article ID 356126, 6 pages doi:10.1155/2012/356126 Research Article Genetic Variations of Glutathione S-Transferase Influence on Blood Cadmium Concentration Nitchaphat Khansakorn,1 Waranya Wongwit,1 Prapin Tharnpoophasiam,1 Bunlue Hengprasith,2 Lerson Suwannathon,3 Suwannee Chanprasertyothin,4 Thunyachai Sura,5 Sming Kaojarern,5 Piyamit Sritara,5 and Jintana Sirivarasai5, 6 1 Department of Social and Environmental Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand 2 Health Offi ce, Electricity Generating Authority of Thailand, Nonthaburi 11130, Thailand 3 Excellence Service Center For Medical Technology and Quality Improvement, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand 4 Offi ce of Research Academic and Innovation, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand 5 Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand 6 Division of Clinical Pharmacology and Toxicology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand Correspondence should be addressed to Jintana Sirivarasai, rajsr@mahidol.ac.th Received 13 October 2011; Accepted 16 November 2011 Academic Editor: J. J. Stegeman Copyright © 2012 Nitchaphat Khansakorn et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The glutathione S-transferases (GSTs) are involved in biotransformation and detoxification of cadmium