原创力文档Mitochondrial Calcium Uniporter MCU Supports Cytoplasmic Ca2+ Oscillations, Store-Operated Ca2+ Entry and Ca2+-Dependent Gene Expression in Response to Receptor Stimulation.PDFVIP
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Mitochondrial Calcium Uniporter MCU Supports Cytoplasmic Ca2+ Oscillations, Store-Operated Ca2+ Entry and Ca2+-Dependent Gene Expression in Response to Receptor Stimulation.PDF
Mitochondrial Calcium Uniporter MCU Supports
Cytoplasmic Ca2+ Oscillations, Store-Operated Ca2+ Entry
and Ca2+-Dependent Gene Expression in Response to
Receptor Stimulation
Krishna Samanta, Sophie Douglas, Anant B. Parekh*
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
Abstract
Ca2+ flux into mitochondria is an important regulator of cytoplasmic Ca2+ signals, energy production and cell death
pathways. Ca2+ uptake can occur through the recently discovered mitochondrial uniporter channel (MCU) b
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