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Journal of Consulting and Clinical Psychology Copyright 2005 by the American Psychological Association
2005, Vol. 73, No. 1, 38–46 0022-006X/05/$12.00 DOI: 10.1037/0022-006X.73.1.38
Potential Mediators of Cognitive–Behavioral Therapy for Adolescents With
Comorbid Major Depression and Conduct Disorder
Noah K. Kaufman Paul Rohde, John R. Seeley, Gregory N. Clarke,
Medico Psychological Services and Eric Stice
Oregon Research Institute
Several possible mediators of a group cognitive–behavioral therapy (CBT) for depressed adolescents
were examined. Six measures specific to CBT (e.g., negative cognitions, engagement in pleasurable
activities) and 2 nonspecific measures (therapeutic alliance, group cohesion) were examined in 93
adolescents with comorbid major depressive disorder and conduct disorder who were randomly assigned
to the Adolescent Coping With Depression (CWD-A) course or a life skills control condition. Change on
the Automatic Thoughts Questionnaire (S. D. Hollon P. C. Kendall, 1980) appeared to mediate
treatment effects on depressive symptoms. Therapeutic alliance by the 3rd session was higher among the
CWD-A participants but did not predict reductions in depressive symptoms. Findings suggest that
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