妊娠期糖尿病孕血清及皮下脂肪组织中视黄醇结合蛋白4表达与胰岛素抵抗的关系.pdfVIP

关键词：RBP4；糖尿病，妊娠：胰岛素抗药性：脂肪组织 Correlationofretinol inserumand bindingprotein4expression subcutaneoustissuewithinsulin adipose resistancein diabetesmellitus． Abstract To thecorrelationofthe ofretinol 4 Objectiveinvestigate expressionbindingprotein inserumandsubcutaneous tissuewithinsulinresistancein diabetes adipose gestational mellitus．MethodsFrom to 2008 womenwith diabetes May 2009，32 April gestational mellitus whodeliveredinthe of of DepartmentObstetrics，Affiliated HospitalQingdao Medical recruitedfor diabetesmellitus UniversityCollege，were gestational group．And 30 women as healthypregnantweretakencontrol group．Enzyme—linked usedtomeasurethe concentrationsofRBP4these assay(ELISA)Was plasma in women． Radio used Was tomeasurethe levelsof immunity assay plasma fastinginsulin(FINS)． measured calculatedthe Fastingplasmaglucose(FPG)Was oxidase,and byglucose homemodelinsulinresistance index(HOMA—IR)．Reverse transcriptionpolymerase chain Westernblotwereusedto the of reaction(RT-PCR)and