滋阴清热法治疗性肾小球肾炎的临床研究.pdfVIP

Clinical Research on Treatment of Chronic Glomerulonephritis with Nourishing Yin and Clearing Heat Speciality：Internal medicine of Traditional Chinese Medicine Author：Qu Zongxu Tutor：Prof.Yu Junsheng Abstract Objective：In order to observe the clinical effect of the treatment with nourishing Yin and clearing heat for chronic glomerulonephritis，and the treatment is implemented mainly through Modified Zhuyeshigao and Erzhidihuang soup, explore its mechanism according to the perspective of modern medicine. Methods：72 patients diagnosed the chronic glomerulonephritis were randomly classified into two groups．Both the two groups were treated with Angiotensin Ⅱ receptor blockers to control the blood pressure. 36 patients were treated with Modified Zhuyeshigao and Erzhidihuang soup in treated group; others were treated with Shenyankangfu tablet in control group. Two months were a course of treatment. Both groups were taking a course of treatment. Result：The patients’ clinical symptoms total score of treatment group was significantly reduced, significantly better than the control group (P0.01). The 24h urinary protein of treatment group were significantly lowered, significantly better than the control group (P0.05). The patients’ hypersensitive C-reactive protein , urine protein, urine occult blood, blood urea nitrogen, serum creatinine of treatment group were significantly reduced, more effective than the control group (P0.05). There was little difference of Lipids, blood pressure, C3 between the two groups, and there was no statistically significance（P＞ 0.05）.Conclusion：The treatment with nourishing Yin and clearing heat which was implemented mainly through Modified Zhuyeshigao and Erzhidihuang soup for chronic glomerulonephritis is more effective than Shenyankangfu tablet. Key words chronic glomerulonephritis; treatment of traditional Chinese medicine; nourishing