中医药干预慢性劳综合征的系统评价.pdfVIP

对 11 篇组间均衡性良好且以西药干预为对照的随机对照试验临床疗效观察文献 进行 Meta 分析，结果显示与西药对照组相比，无论中成药还是中药干预，治疗组均 优于对照组，差异有统计学意义。 结论：虽目前关于中医药干预慢性疲劳综合征临床疗效观察文献较多，但临床随 机对照试验的数量仍较少，且存在不少问题。Meta 分析结果表明中医药干预慢性疲 劳综合征疗效优于西药干预，且益气养血、温肾健脾疏肝法更为有效，但本次纳入文 献的质量偏低且存在发表性偏倚等问题，对结果可靠性及真实性产生了一定影响。所 以，为求更有力的循证依据，希望将来有更多更高质量的完全随机对照临床试验的文 献报道。 关键词 慢性疲劳综合征；中医药；系统评价；Meta分析 A SYSTEMATIC REVIEW OF TCM IN TREATING CHRONIC FATIGUE SYNDROME Speciality：Internal Medicine of TCM Author ：Jiang Xijuan Tutor：Prof Peng Wei ABSTRACT Objective: To systematically realize the problems in the TCM clinical researches of CFS, and to evaluate the quality of these researches. To make the systematic review of the curative effect of TCM treatment to the CFS, so that clinical treating decision can be based on objective believable evaluation of the treatment. Methods: Use the data base to searches literatures during 2002~2011 years ．Investigate the clinical effect of TCM that it helps the CFS ．According to inclusion-criteria and exclusion-criteria,filtrate the literatures．Based on the principle and the method of DME, formulate the Systematic Review Table of the treatment article of TCM to the CFS. It has made statistic analysis from several aspects．Calculate the percentage 0f all kinds of states and evaluate the quality．Then utilize the RevMan5.0 to procee Meta analysis． Result:I have recalled the literatures about the TCM treatment to the CFS 2594 piecesin all,only 38 clinical controlled trials in line with the inclusion criteria and exclusion criteria.In diagnostic criteria,there are 12 pieces(31.58%)adopting the TCM diagnosis with Western medicine diagnostic criteria; 21 pieces(55.26%) only adopting the Western medicine diagnostic crite