养心舒脉汤对慢心力衰竭患者raas系统影响的研究.pdfVIP

The Clinical Study the Infection of CHF Patients’ RAAS System by the Yang Xin Shu Mai Decoction Speciality: Internal Medicine of Traditional Chinese Medicine Author : SONG YANjie Tutor: Professor Tang Keqing Abstract Objective: through clinical observation, study and discussion in treatment of chronic heart failure(CHF) disease, if the effect of experimental grou-- Yang Xin Shu Mai Decoction which uses ‘Both Wenyang and Ziyin’ method will be obviously better than the control group Li Qiang Xin Capsule which uses ‘Wenyang Only’ method.Methods: 60 patients with CHF were randomly divided into the experimental group 30 cases, and they will be given Yangxin Shu Mai decoction combined with routine western medicine therapy. At the same time ,the other 30 cases of the control group will be given Qi Li Qiang Xin Capsule combined with routine western medicine therapy also.The course of treatment is 14 days.To observe the change between the two groups in clinical symptoms and laboratory test indexes. Results:After the clinical observation, experimental group’ treatment scheme can strongly improve patients’ heart function ,reduce renin activity (PRA),angiotensinII (AngII) and aldosterone(ALD) concentration of the RAAS system. At the same time,improve syndrome of Traditional Chinese Mdecine(TCM),improve the numerical value of Left Ventricular Ejection Fraction(LVEF) and change the NYHA heart function classification. After statistics analysis, it’s clear that the effects of two groups have significant difference, which means the results have statistical significance. Conclusion: Yang Xin Shu Mai Decoction has great effect upon improving CHF patients’ heart function and inhibiting the activity of the RAAS system. This study compares and proves the curative effect of ‘Both Wenyang and Ziyin’ method, and enrich the theory of application of TCM i