瘢痕灸足三里治腹泻型肠易激综合征的临床疗效观察与机理研究.pdfVIP

The Clinical Observation and Mechanism of The Scarring-moxibustion Therapy on ST36 Acupoint In Treating of Diarrhea Irritable Bowel Syndrome Specialty：Acupuncture of TCM Author ：Mengzhen Tutor：Professor YangDianhui Abstract Objective To observe the clinical effect of scarring-moxibustion therapy on ST36 acupoint in treating diarrhea irritable bowel syndrome, and investigated the working mechanism of colon disfunction. Methods This study included the parts of animal experiments and human experiments. Divided 40 patients into 2 groups in the human experiments. Group one is treated with scarring-moxibustion therapy. Group two is treated with acupuncture therapy. The question of adequate relief and irritable bowel symptom severity score were counted for an evaluation of the therapeutic effects. Wistar female rats have been used in this study, and post infectious irritable bowel syndrome(PI-IBS) model was selected in the animal experiments. We were prepared to observe the contractile activity of the colonic smooth muscle strips before and after scarring-moxibustion therapy on ST36 acupoint. Results The question of adequate relief and irritable bowel symptom severity score have great significance difference before and between control group and treat group （P0.05 or P0.01）. Comparing with IBS model group, the contractile amplitude, frequency and tension of uterine smooth muscle strips is obviously reduced after scarring-moxibustion therapy. Conclusions Scarring-moxibustion therapy on ST36 acupoint has fairly good clinical effectiveness for diarrhea irritable bowel syndrome, inhibited the colon contractile activity and improved the time of defection. Keyword Diarrhea irritable bowel syndrome; Scarring-mox