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系统评价清热祛法治疗慢性乙型肝炎的临床疗效研究
A Systematic Review of Chronic Hepatitis B
Speciality:Basic Theory of TCM
Author:Zhang Tiefeng
Tutor:Prof.Meng Lingjun
Abstract
Objectives: Carry on qualitative and the quantitative analysis on randomized
controlled trials (RCT) of clearing away heat and expelling dampness to therapies for
chronic hepatitis B since 1994 to 2008 with Evidence-based medicine method,providing
the best proof for the clinical reatment ,and lay foundation for carrying on further study.
Method:(1) With the searching terms,pick out the titlerecords of Traditional Chinese
Medical (TCM) therapyies for chronichepatitis B which including the words random.(2)
Randomised or quasi randomised clinical trials of TCM therapies for chronic hepatitis B
were selected for this study. (3) The evidence-based medicines method will be abided by
for the study. The evaluation of methodological quality of clinical trials will be carried on
according to the request of Cochrane manual , including allotment method of
randomization ,concealment of allocation sequence,blind method ,withdraw or lose to visit
case number and reason,intention-to-treatanalysis and so on.
Main results: 501 articles were found from881pieces of title recordsconcerning this
kind of literature ,40.1% of which took the design of randomized trial control,and last got
236 full texts. randomized clinical trials (RCTs) and pseudo-randomized clinical trials
involving 1616 chronic hepatitis B patients were identified that tested.Traditional Chinese
medical therapeutic effect. The appraisal content mainly includes carrying on the
circumstan-ces and the qualitative analysis on selected ordinary clinicaltrials. Carry on
Meta analysis on selected randomized controlled trials(RCT) about the treatment of CHB
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