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中药防哮饮对哮小鼠血清IL-13含量影响的研究
目 录
中文摘要 ···············································1
英文摘要 ···············································3
引 言 ················································7
正 文 ················································9
1.实验材料及方法 ······································9
1.1 实验动物·············································9
1.2 主要药品和试剂 ·······································9
1.3 主要器材和设备 ·······································9
1.4 药物配制············································10
1.5 实验分组及给药 ······································10
1.6 小鼠哮喘模型的制备··································10
1.7 观测指标和方法 ······································11
1.8 统计学分析 ··········································13
2. 实验结果 ············································13
2.1 各组小鼠一般情况 ····································13
2.2 各组小鼠血清 IL-13 含量的比较 ························14
2.3 各组小鼠骨髓嗜酸性粒细胞百分计数的比较 ··············15
3.讨论 ·················································17
3.1 祖国医学对儿童哮喘的认识 ·····························17
3.2 中药防哮饮组方配伍分析 ·······························19
3.3 现代医学对哮喘病的认识 ··························23
3.4 动物模型的评价 ·······································28
3.5 哮喘早期干预的理论依据 ·······························29
4.存在问题与展望 ········································31
结 论 ···············································32
参考文献 ··············································33
附 录 ···············································38
综 述 ···············································40
致 谢 ···············································50
攻读学位期间发表的学术论文目录 ··························51
广西中医学院研究生学位论文作者声明 ······················52
个人简历 ················································53
中 文 摘 要
目 的：本文通过建立小鼠哮喘模型，观察中药“防哮饮”早期干预
治疗对哮喘小鼠血清白细胞介素-13 （IL-13 ）含量水平的变化以及骨
髓嗜酸性粒细胞（EOS ）百分计数的影响，探讨其防治哮喘的作用机制，
为 “防哮饮”早期干预治疗小儿哮喘的临床应用提供理论和实验依据。
方 法：采用腹腔注射卵蛋白（OVA ）致敏液激发复制小鼠哮喘模型，
将 60 只健康昆明小鼠随机
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