急性肾小球肾炎（agn）.ppt

Nutritional Anemia 营养性贫血 Department of Pediatrics Soochow University Affiliated Children’s Hospital Main Point –要点 Master iron metabolism trait Master clinical features, diagnosis, therapy and prevention of nutritional anemia Know well pathogenesis and laboratory findings of nutritional anemia (一) nutritional iron deficiency anemia, NIDA-营养性缺铁性贫血 1、Introduction-简介 Definition / describing Anemia is defined as a pathological process (syndrome) in which hemoglobin (Hb) concentration in red cells is abnormally low, considering variations as to age, gender, sea-level altitude, as a result of several situations such as chronic infections, hereditary blood conditions, deficiency of one or more essential nutrients that are necessary for the formation of hemoglobin e.g.: folic acid, B12, B6 and C vitamins, and proteins. Therefore, there is no doubt that iron deficiency is the cause of most anemia. It is called iron deficiency anemia. The anemia caused by insufficient dietary iron uptake, in which the iron storage and hemoglobin synthesis decreased. Clinical characteristics-临床特征 ? iron stores ? serum iron ?hemoglobin concentration , hypochromic microcytic anemia good response to iron therapy 6mo to 3 yrs 2、IRON METABOLISM-铁代谢 CONTENTS New born 75mg/kg Children35-70mg/kg Adults M 50mg/kg F 35mg/kg CMOPARTMENT Hemoglobin 64% Storage iron 30% ferritin hemosiderin Myloglobin 3% Enzyme iron 0.4% Serum iron 0.4% Iron sources-铁来源 Hemoglobin iron Dietary iron Dietary iron-饮食铁 High in iron Red meat/ liver kidney/ oily fish Average iron Beans / fortified cereals/ dark green vegetables/ dried fruit/ nuts and seeds Poor in iron milk Iron absorption-吸收 general absorption 1-20% Meat/ fish/ chicken 10-25% Cereals/vegetables 1% Breast/cow’s milk 50%/10% Iron stores and utilizing-储存和利用 Requirement and excretion –需