10例淀粉样脑血管病相关脑叶出血的临床病理分析.pdfVIP

　 军 杂 20 15年7月1 日　第40卷　第7期 530 解放 医学 志　 10例淀粉样脑血管病相关脑叶出血的临床病理分析 李晓秋，韩雅玲，陈会生 [摘要]　目的　总结10例尸检证实的淀粉样脑血管病相关脑叶出血病例的临床资料与病理特点，提高对本病的认 识与诊断水平。方法　回顾性分析沈阳军区总医院从1983年7月－2005年7月收治的10例淀粉样脑血管病相关脑叶出血 患者，总结其临床资料及病理学特点。结果　10例患者中单发脑叶出血2例，多灶性脑叶出血8例，均破入蛛网膜下 腔。病理检查2例见微小动脉瘤，4例见 “双桶”样改变，5例见多发微小动脉丛，4例见闭塞性洋葱皮样内膜改变，7 例见血管壁类纤维素坏死。8例见不同程度的神经原纤维缠结，5例见老年斑。结论　淀粉样脑血管病相关脑叶出血多 分布在顶叶、颞叶、枕叶，常为多发性、复发性脑叶出血，易破入蛛网膜下腔。淀粉样脑血管病相关微血管病变可能 是脑叶出血的重要病理基础。 [关键词]　脑淀粉样血管病；脑出血；病理学，临床 [中图分类号]　R597.2　　　　[文献标志码]　A　　　　[文章编号]　0577-7402 (20 15)07-0530-05 [D OI]　10. 11855/j.issn.0577-7402.20 15.07.04 Clinical and pathological study on 10 cases of cerebral lobe hemorrhage related with cerebral amyloid angiopathy 1 2* 1* LI Xiao-qiu , HAN Ya-ling , CHEN Hui-sheng 1 2 Department of Neurology, Department of Cardiology, General Hospital of Shenyang Command, Shenyang 110840, China * Corresponding authors. CHEN Hui-sheng, E-mail: chszh@; HAN Ya-ling, E-mail: hanyaling@263.net This work was supported by the Key Science and Technology Program of Liaoning Province(2013225089) and Ministry of Major New Drug Innovative Drug Research and Open Technology Platform (2012ZX0903016-002) [A b stract]　Obj ectiv e　To summarize th e clinical data and path ol ogical features of 10 cases of cerebral l ob ar h emorrhage rel ated w ith cereb ral amy l oi d angi op athy (CA A ) diagnosed p ath ol ogi cally, th ereby to improv e th e know l edge and diagnosi s of th e di sease. M eth ods　Th e clini cal data of 10 cases of cereb ral l ob ar h em orrh age rel ated w ith CA A , coll ected in th e Gen eral Hosp it al of Sh eny ang Comman d from 1983 up to n ow, w ere retrosp ectiv ely analy zed, an d th e clini cal an d n europ ath ol ogi cal features of th ese cases w ere summarized. Results　Of th e