集束化治疗感染性休克的临床效果分析.docVIP

集束化治疗感染性休克的临床效果分析 　　[摘要] 目的 探讨集速化治疗感染性休克的临床效果分析。方法 随机抽取2011年5月―2012年12月由新疆克州人民医院重症医学科收治的60例感染性体克患者的病例。分别为对照组30例和观察组30例，对照组采用常规治疗，观察组采用集束化治疗，采用6 h和24 h感染性休克集速化治疗，对照两组的临床疗效。结果 ①在6 h的集速化治疗中：观察组与对照组相比，观察组的患者在入重症科后，初步确诊的时间、抗生素治疗前获取血培养的实施率、血清乳酸测定率、2 h内置入中心静脉导管、1 h内给予经验性抗生素治疗、应用血管活性药物、6 hEGDT 达标率差异具有统计学意义（P0.05）。 结论 以6 h和24 h感染性休克集速化治疗为核心的临床途径，可以提高ICU 医师对SSC指南的操作，降低患者感染性休克的死亡率与感染率。 中国论文网 /6/view-7159700.htm 　　[关键字] 集束化治疗；感染性；休克 　　[中图分类号] R631+4 [文献标识码] A [文章编号] 1674-0742（2015）10（a）-0104-02 　　Analysis of Clinical Effect of Bundle Treatment for Septic Shock 　　ZHANG Xi 　　ICU， Kezhou People’s Hospital， Kezhou， Xinjiang Uygur Autonomous Region， 845350 China 　　[Abstract] Objective To investigate the clinical effect of bundle treatment for septic shock. Methods 60 patients with septic shock admitted to the ICU of Kezhou People’s Hospital between May 2011 and December 2012 were randomly selected. They were assigned to undergo conventional therapy （the control group， n=30） and 6h and 24h bundle group （the observation group， n=30）. The clinical efficacy was compared between the two groups. Results In the 6h bundle treatment， in terms of preliminary diagnosis time， blood culture before the use of antibiotics， detection rate of serum lactic acid， central Venous Catheterization within 2h， empirical antibiotics treatment within 1h， use of vasoactive agents， 6hEGDT compliance rate， there was statistically significant difference between the two groups（P0.05）. In the 24 h bundle treatment， in terms of blood glucose control， use of small dose of glucocorticoid， and protective lung ventilation strategy， there was statistically significant difference， P0.05. In terms of duration of mechanical ventilation and lengthy of ICU stay， there was no statistically significant difference between the two groups， P0.05. Conclusion The clinical therapeutic approach with 6h and 24h bundle treatment in the core can improve ICU physician’s performance according to the SSC guide， and reduce the mortalit