FDA咨询小组建议禁用含对乙酰氨基酚的复方镇痛药.docVIP

FDA 咨询小组建议禁用含对乙酰氨基酚的复方镇痛药 2009年6月30日美国食品和药物管理局（FDA）咨询小组建议，禁止并且从美国市场上撤下目前广泛使用的两种处方镇痛药Percocet （羟考酮/对乙酰氨基酚）和 Vicodin（氢可酮 /对乙酰氨基酚）。 这些药品所含的对乙酰氨基酚（解热镇痛药）有造成肝脏严重受损的风险。 在美国，因服用这类药物过量，每年造成超过四百人死亡，四万两千人住院。 如果FDA接受这一建议，这两种处方镇痛药Percocet （羟考酮/对乙酰氨基酚）和 Vicodin（氢可酮 /对乙酰氨基酚）将在美国市场上被禁止使用。 Dr. Carol Cunningham ，紧急医疗服务医务主任说，服用对乙酰氨基酚超量引起严重危害的原因主要有：一、患者大量服用对乙酰氨基酚，因为他不了解对乙酰氨基酚的副作用以及对肝脏的损害； 二、患者同时服用含有对乙酰氨基酚的复方镇痛药，造成无意的超量服用。 三、患者本身存在像肝硬化等危险因素，更容易因服用对乙酰氨基酚造成严重的肝脏损害。 Dr. Carol Cunningham 还表示，医生应仔细询问、检查患者的病情，确保给患者使用合适的药物，避免造成不必要的、严重的副反应。 Dr.Begley 说 从2008开始，因服用对乙酰氨基酚引起的意外死亡事件呈现的下降趋势， 是因为更多的医生选择了处方OxyCodone，因其不含对乙酰氨基酚。 窗体顶端 窗体底端 Serving Northern Ohio 窗体底端 By Jason Lea JLea@News-H A panel for the Food and Drug Administration has recommended removing prescription drugs that combine acetaminophen with stronger painkillers from the market.If the FDA were to accept this suggestion, drugs like Percocet or Vicodin would no longer be available.The panel voted 20-17 in favor of the recommendation, stating the prescription drugs have led to several overdose deaths.Cunningham said some patients needed to use acetaminophen products because they have pre-existing medical conditions or allergies that preclude other painkillers.Cunningham said acetaminophen-related overdoses occur mostly for three reasons. One, a person takes too much acetaminophen, not realizing that it is toxic and can damage their liver. Two, a person was using the opiate ingredients in the painkillers to get high and took too much. Third, a person has a medical condition like cirrhosis that makes them more vulnerable to the harmful side effects of acetaminophen.She approved of the same FDA panels vote to put a black box warning, the most serious safety label, on the drugs packaging should they stay on the market.The panel voted for the black box warning with an overwhelming 36-1 majority.I dont think the average person is knowledgeable about what acetaminophen