CRISPRCas9技术重点分析.pptVIP

CRISPR/Cas9系统及其应用 Introduction and Applications of CRISPR-Cas9 for Genome Engineering Anliang Dong Apr.16th,2015 CRISPR-Cas系统简介 CRISPR-Cas系统的应用技术 CRISPR-Cas系统的应用前景 What is the CRISPR/Cas？ CRISPR/ Cas ---- Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated proteins CRISPR loci Consist of the signature CRISPR array and CRISPR-associated (Cas) genes CRISPR array a series of repeat sequences (direct repeats) interspaced by variable sequences (spacers) corresponding to sequences within foreign genetic elements (protospacers) CRISPR arrays are first transcri