儿童急性早幼粒细胞白血病临床的研究.pdf

儿童急性早幼粒细胞白血病临床研究 Aclinicalforchildhoodwithacute leukemia study promyelocytic Toevaluatetheclinical and [Abstract]0bjective outcomeofacute Since promyelocyticleukaemia(APL)in than18 APLwere November included． 1991，102 years)proven children(younger Fourteenfailedtobetreatedduetotheeconomicalreason．Datafromothers patiems were 10．0 software．Result analyzed耐出SPSSsystem Sixty-one 41 in was wereincludedthis median gifts age缸diagnosis13(3 00．2％1 study．The -1 oldChildhoodAPLwerecharacterized fever． 8)years by TheWBCcountat w鹤morethan10×10讥，iIl32 presentation immunophenotypeofAPLwas thelow CD64、CD38、CDll7、H1T4(CD99R)andexpress studiesdemonstratedcharacteristictranslocationinabout Cytogenetic the 15；17 643％ofthe56 Ct caseswas93．8％ofthe64 patientsanalyzed，PML／RARpositive didnotinfluencetheoutcomeof patientsanalyzed_Additionalcytogeneticchanges allATRA with acute leukemiatreatedwith patiems diagnosed newly promyeloeytic