脑电和脑磁研究中的动态因果模型教材.ppt

Dynamic Causal Modelling of Evoked Responses in EEG/MEG Wellcome Dept. of Imaging Neuroscience University College London Fit to scalp data observed predicted Conclusions Dynamic Causal Modelling (DCM) for EEG/MEG is physiologically grounded model. Context-induced differences in ERPs are modelled as modulation of connectivity between areas. Spherical head model is useful spatial model. DCM can alternatively be seen as source reconstruction device with temporal constraints. In the same way like SPM for fMRI Use SPM2‘s methods! However, model needs to be adapted to make proper inference Comparison with fMRI analysis to aid illustration Also, conventional model (to be shown) in the same framework In the same way like SPM for fMRI Use SPM2‘s methods! However, model needs to be adapted to make proper inference Comparison with fMRI analysis to aid illustration Also, conventional model (to be shown) in the same framework In the same way like SPM for fMRI Use SPM2‘s methods! However, model needs to be adapted to make proper inference Comparison with fMRI analysis to aid illustration Also, conventional model (to be shown) in the same framework t-contrast: tests for single dimension in parameter space F-contrast: tests for multiple dimensions inference at first or second level (fixed or random effects) over conditions or groups: main effect, difference, interaction: average over time window parametric modulation with extrinsic variable power comparison in time-frequency domain t-contrast: tests for single dimension in parameter space F-contrast: tests for multiple dimensions inference at first or second level (fixed or random effects) over conditions or groups: main effect, difference, interaction: average over time window parametric modulation with extrinsic variable power comparison in time-frequency domain t-contrast: tests for single dimension in parameter space F-contrast: tests for multiple dimensions inference at first or second level (fixed or random effects) over