GenomeWideAssociationStudiesForCommonDiseaseandComplex剖析.ppt

Genome-Wide Association Studies For Common Disease and Complex Traits 2005.7.12 ????? ??? Contents What is Association Study? Why Genome-wide association studies? What has made these studies possible? Markers for genome-wide Association Studies. Allelic spectra of common disease Strategies to increase efficiency Avoiding false positive association Analyzing gene-gene interactions Conclusions and future directions Glossary Linkage Disequilibrium Haplotype Penetrance Heritability Population stratification SNPs LD blocks Tag SNPs What is Association Study? Association study Assess correlations