33Lesson5-BoneTumor精编.ppt

BONE TUMOR General Consideration A bone tumor ?is an abnormal growth of cells within the bone that may be benign or malignant Incidence is relatively low. Reasons remain unclear. CLASSIFICATION Mesoderm (differentiation) Osteoblast osteoclast chondroblast fibroblast collagenoblast musculoskeletal system BONE TUMORS IN THE REALM OF NEOPLASIA Named by the tissue of origin + the suffix:oma for benign sarcoma for malignant. WHO Classification BONE-FORMING TUMORS CARTILAGE-FORMING TUMORS GIANT-CELL TUMOR(OSTEOCLASTOMA) MARROW TUMOR(ROUND-CELL TUMOR) VASCULAR TUMOR OTHER CONNECTIVE TISSUE TUMOR OTHER TUMOR TUMORLIKE LESION WHO Classification BONE-FORMING TUMORS A. Benign 1. Osteoma 2. Osteoid osteoma and osteoblastoma B. Intermediate Aggressive (malignant) Osteoblastoma C. Malignant Osteosarcoma A. Central (medullary) B. Surface (peripheral) 1. Parosteal 2. Periosteal 3. High-grade surface WHO Classification A. Benign 1. Chondroma a.Enchondroam b.Periosteal (juxtacortical) 2. Osteochondroma (osteocartilaginous exostosis) a.Solitary b.Multiple hereditary 3. Chondroblastoma (epiphyseal chondroblastoma) 4. Chondromyxoid fibroma B.Malignant 1. Chondrosarcoma (conventional) 2. dedifferentiated chondrosarcoma 3. Juxtacortical (periosteal) chondrosarcoma 4. Mesenchymal chondrosarcoma 5. Clear-cell chondrosarcoma 6. Malignant chondrosarcoma CARTILAGE-FORMING TUMORS WHO Classification GIANT-CELL TUMOR(OSTEOCLASTOMA) WHO Classification MARROW TUMOR(ROUND-CELL TUMOR) 1. Ewing sarcoma of bone 2. Malignant lymphoma of bone 3. Myeloma WHO Classification VASVULAR TUMOR . Benign 1. Hemangioma 2. Lymphangioma 3. Glomus tumor (glomangioma) Intermediate or Indeterminate 1. Hemangioendothelioma(epithelioid hemangioendothelioma,histiocytoid h