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请仔细校对后,于4月24日前发回! 注意文中批注部分 修改的地方用红色字体标注 建议补充本刊2-3条参考文献 儿童腺样体肥大致肺动脉高压3例并 右心导管检查分析 The analysis of right heart catheterization results on 3 children with pulmonary hypertension caused by adenoids hypertrophy 周红梅 尚小珂 Liang Zhong 彭婷 邓晓娴 张刚成 基金项目:国家“十二.五”科技支撑项目 肺循环疾病及其心功能研究(项目编号:2011BAI11B15) 作者单位:430022 湖北省武汉市,武汉亚洲心脏病医院心外科导管室 国家肺动脉高压诊疗基地 国家结构心脏病介入培训基地(周红梅、尚小珂、彭婷、邓晓娴、张刚成); 新加坡国立心脏中心 新加坡国立心脏研 究所 国立大学医学研究院生物研究所(Liang Zhong) 通讯作者:尚小珂,E-mail 【摘要】 目的 分析近年来收治的肺动脉高压合并腺样体肥大致睡眠呼吸暂停综合征病例的临床资料,为临床诊治提供经验。方法 对武汉亚洲心脏病医院自2012年至2014年收治的肺动脉高压病例的临床资料及随访结果进行回顾性分析,其中3例为腺样体肥大致睡眠呼吸暂停综合征并肺动脉高压。结果 3例右心导管结果mPAP(33.33±10.06)mm Hg,PVR(1015±606.66)dyn·s-1·cm-5,经治疗后复查活动能力均明显改善,心功能改善。结论 腺样体肥大致肺动脉高压行病因治疗联合靶向药物波生坦口服安全有效。 【关键词】 腺样体肥大; 肺动脉高压; 睡眠呼吸暂停 The analysis of right heart catheterization results on 3 children with pulmonary hypertension caused by adenoids hypertrophy ZHOU Hong-mei*, SHANG Xiao-ke, LIANG Zhong, et al. *Cardiac Surgical Interventional Cath Lab Wuhan Asia Heart Hospital, Wuhan 430022, China Corresponding author:SHANG Xiao-ke, E-mail 【Abstract】 Objective To analyze the clinical data of patients with pulmonary hypertension companied with sleep apnea syndrome caused by adenoids hypertrophy in recent years and provide experience for clinical diagnosis and treatment. Methods We retrospectively analyzed the clinical data and follow-up results of patients with pulmonary hypertension hospitalized at Wuhan Asia Heart Hospital from 2012 to 2014, including three cases with sleep apnea syndrome caused by adenoids hypertrophy. Results The right heart catheterization results of these 3 cases were as follows:mPAP was (33.33±10.06)mm Hg, PVR was (1015±606.66)dyn·s-1·cm-5, and after targeted therapy the patients′ exercizing abililty and heart function had been significantly improved. Conclusion Etiology therapy combined bosentan, a targeted drug was a safe and effective treatment f

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