05UnitSixBiochemistry2014课稿.pptVIP

Biochemistry Dr. Zhuofeng Lin School of Pharmacy, Wenzhou Medical College Company Logo Contents Special Terms 1 Text A: Many Biological Functions of Proteins 2 Passage B: Cell, Biological Units of Molecular Organization 3 Review Pre-view 4 activation 激活作用 agonist 兴奋剂；激动剂 anabolism 合成代谢 antibody 抗体 antigen 抗原 biochemistry 生物化学 Special terms biologic oxidation 生物氧化 biotransformation 生物转化 catabolism 降解代谢，分解代谢 chromatin 染色质 configuration 构型 conformation 构象 Special terms conjugated protein 结合蛋白 deactivation 失活（作用） degradation 降解作用 diabetes mellitus 糖尿病 energy metabolism 能量代谢 genome 基因组 Special terms hormone 激素 immunity 免疫性 immune response 免疫反应 macromolecule 大分子 metabolism 代谢 metabolic antagonist 代谢拮抗物 Special terms metabolic regulation 代谢调节 nutrition 营养 oncogene 致癌基因 oxidoreductase 氧化还原酶 renaturation 复性；复原 subunit 亚基；亚单位 Special terms transfection 转染 transcription 转录 transduction 转导 vector 载体 Special terms Text A—protein functions What are Proteins? Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. Myoglobin, 3D structure /wiki/Protein Enzymes What are enzymes?? Enzymes are proteins that catalyze (i.e., increase the rates of) chemical reactions. How classified a enzymes? Enzymes are systematically classified according to the nature of reaction that they catalyze. The formal name, common name, other… Ex: Trysin from pancreas acinar cell. Text A: Many Biological Functions of Proteins Regulatory Proteins A type of protein that can regulate the ability of other proteins to carry out their physiological functions. Examples: insulin a hormone regulate glucose metabolism in animals. Text A: Many Biological Functions of Proteins Characteristics of Regulatory Protein Act by binding to DNA sequence that are adjacent to coding regions