Ncpap联合小剂量酚妥拉明治疗老年重症肺炎疗效观察.docVIP

Ncpap联合小剂量酚妥拉明治疗老年重症肺炎疗效观察 　　x摘要] 目的 观察经鼻持续气道正压通气（Ncpap）联合小剂量酚妥拉明治疗老年重症肺炎的临床效果。 方法 选取2013年2月～2014年1月于我院诊治的重症肺炎老年患者共95例，随机原则分为对照组47例和观察组48例，对照组实施常规治疗联合Ncpap，观察组实施常规治疗联合Ncpap和小剂量酚妥拉明治疗。比较两组患者的各项临床症状改善时间、住院时间、血气指标变化、治疗总有效率。 结果 观察组各项临床症状（肺部??音、气促、紫绀、肝脏回缩）消失时间和住院时间均显著短于对照组（P0.05）；治疗12 h后，两组患者的各项血气指标（PaO2、PaCO2）均较治疗前改善明显（P0.05），且观察组血气指标改善优于对照组（P0.05）；观察组和对照组的治疗总有效率分别为95.8%和85.1%，观察组高于对照组（P0.05）。 结论 对临床重症肺炎的老年患者实施Ncpap联合小剂量酚妥拉明治疗，患者症状改善快，住院时间短，效果显著，值得推广。 　　[关键词] Ncpap；酚妥拉明；小剂量；重症肺炎 　　[中图分类号] R563.1 [文献标识码] B [文章编号] 1673-9701（2015）11-0029-03 　　[Abstract] Objective To observe the clinical effect of nasal continuous positive airway pressure （Ncpap） combined with small dose of phentolamine in treatment of elderly patients with severe pneumonia. Methods A total of 95 cases of elderly patients with severe pneumonia in our hospital from February 2013 to January 2014 were chosen. And they were randomly divided into the control group（47 cases） and the observation group（48 cases）. The control group received the routine therapy combined with Ncpap， while the observation group was given the conventional treatment combined with Ncpap and small dose phentolamine treatment. The clinical symptom improvement time， the hospitalization time， blood gas index changes， the total efficiency of treatment in two groups were compared. Results The clinical symptoms disappeared time（pulmonary rales， shortness of breath， cyanosis， liver retraction） and hospital stay of the observation group were significantly shorter than those in control group （P0.05）； After treatment 12 h， the blood gas（PaO2， PaCO2） in patients of the two groups were improved significantly than before treatment（P0.05）； And observation group blood gas improved better than the control group（P0.05）； The total effective rate of the observation group and the control group was 95.8% and 85.1%， the total effective rate of observation group was higher than control group （P0.05）. Conclusion Ncpap combined with small dose phentolamine