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不同类型脑梗死患者急性期血压调控对预后的影响.doc
不同类型脑梗死患者急性期血压调控对预后的影响 【摘要】 目的:探讨不同类型脑梗死患者急性期血压调控对预后的影响。方法:将162例脑梗死急性期患者随机分为对照组(n 95)与干预组(n 67),对照组患者均常规应用阿司匹林、钙拮抗剂,并辅以胞二磷胆碱进行对症支持性治疗,干预组在对照组基础上采用药物进行降血压治疗,使患者入院1 d内的血压下降至160/100 mm Hg内,采用NIHSS评分、Barthel Index评分及改良Rankin评分比较两组患者入院时、治疗第1周、治疗半年及治疗1年时的评分情况。结果:干预组治疗第1周的Barthel Index评分为(46.3±12.8)分,显著低于对照组的(49.1±13.3)分,差异有统计学意义(P 0.05);干预组治疗半年及1年后的NIHSS评分、Barthel Index评分及改良Rankin评分显著低于对照组同期水平(P 0.05或P 0.01);干预组治疗1周后的TACI、PACI、POCI型Barthel Index评分均显著低于对照组水平(P 0.05);治疗1周后TACI型的改良Rankin显著高于对照组(P 0.05);治疗半年后LACI、TACI、PACI、POCI的Barthel Index评分显著低于对照组(P 0.05或P 0.01);治疗半年后TACI、PACI型的NIHSS评分显著高于对照组(P 0.05或P 0.01)。结论:脑梗死急性期早期进行降血压治疗预后效果往往不良。 【关键词】 OCSP; 脑梗死; 急性期; 血压调控; 预后 Efficacy of Acute Blood Pressure Regulation Treat for Different Types Cerebral Infarction Prognosis/CHEN Feng,PENG Mu-li,LIANG Guo-hua,et al.//Medical Innovation of China,2015,12(18):008-011 【Abstract】 Objective:To explore the efficacy of acute blood pressure regulation in different types cerebral infarction prognosis.Method:162 patients with acute cerebral infarction were randomly divided into the control group(n 95) and the intervention group(n 67).The control group patients patients were treated with routine use of aspirin,calcium antagonists,and supplemented citicoline be symptomatic and supportive treatment.The intervention group were treated with drugs for lowering blood pressure on the basis of the control group.Decreased blood pressure in 160/100 mm Hg in 1 day after admission.The NIHSS score,Barthel Index score and modified Rankin scores were compared at admission,the first week after treatment,six months after treatment and and 1 year after treatment between the two groups.Result:The Barthel Index score at the first week after treatment(46.3±12.8) points vs (49.1±13.3) points in the intervention group were significantly lower than the control group(P 3 讨论 本研究对所有符合入选条件的脑卒中患者均采用OCSP进行分型,OCSP分型是1991年由英国的Banford依据急性脑梗死患者的解剖及病理生理过程进行的分型方法,其最大的优点在于方法简便,不依赖CT及MRI的检查结果,通过患者的临床表现(全脑症状及局部病灶损伤症状)进行迅速分型,并一定程度提
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