子痫前期胎儿血流检测与围生儿预后分析.docVIP

子痫前期胎儿血流检测与围生儿预后分析 　　[摘要] 目的 探讨子痫前期胎儿血流检测与围生儿预后分析。 方法 我院于2012年7月～2014年7月对120例妊娠20周后的孕妇进行回顾性研究，分为研究组和对照组各60例，研究组为子痫前期胎儿；对照组为正常妊娠胎儿。两组均采用彩色多普勒超声仪于24周～27周+6、28周～31周+6、32周～分娩前进行检测：静脉导管及脐静脉、脐动脉及大脑中动脉血流的各项参数变化，并与围产儿预后情况进行比较分析。 结果 无论轻度还是重度子痫胎儿阻力指数（RI）、静脉导管的前负荷指数（PLL）、峰值流速指数（PVIV）、搏动指数（PIV）、静脉导管分流率（Qdv-静脉导管血流量/Quv-脐静脉血流量）的数值均明显高于对照组，差异具有统计学意义（P0.05）。结论 子痫前期胎儿的静脉导管及脐静脉血流异常或波形改变与围产儿不良结局存在一定关系。 　　[关键词] 子痫前期；胎儿血流；围生儿预后 　　[中图分类号] R722.1 [文献标识码] B [文章编号] 1673-9701（2015）15-0034-03 　　[Abstract] Objective To study the prognosis in preeclampsia fetal blood flow detection and perinatals analysis. Methods From July 2012 to July 2014， 120 cases of pregnant women at 20 weeks of gestation conducted a retrospective studied in our hospital， were divided into the research group and the control group（n=60）， the research group was preeclampsia fetus； The control group was normal pregnancy fetus. Two groups all used color doppler ultrasound instrument from 24 weeks-27 weeks+6， to 28 weeks -31 weeks+6，32 weeks to be tested before delivery： venous catheter and umbilical vein， umbilical artery and middle cerebral artery blood flow parameters change， and perinatal prognosis were analyzed. Results Both mild and severe pre-eclampsia fetal resistance index（RI）， venous catheter before load index（PLL）， peak flow velocity（PVIV）， pulse index（PIV）， intravenous catheter FenLiuLv（Qdv-venous catheter blood flow/Quv-umbilical venous blood flow） values were significantly higher than that of control group， the difference was statistical significant（P0.05）； Two groups of umbilical vein between pH and umbilical arterial blood oxygen saturation had no obvious difference （P0.05）. Conclusion Preeclampsia fetal abnormal venous catheter and umbilical vein blood flow or waveform changes have a certain relationship with poor perinatal outcomes. 　　[Key words] Preeclampsia； Fetal blood flow； Perinatal prognosis 　　妊娠期高血压疾病发病率高达10%左右，迄今为止，仍为孕产妇及围生儿死亡的重要原因。目前超声通常采用检测脐动脉、大脑中动脉血流来监测胎儿缺氧情况，但相当一部分胎儿在缺氧、生长受限时其血流检测值仍在正常范围