急性期血糖水平对脑梗死患者近期预后的影响.docVIP

急性期血糖水平对脑梗死患者近期预后的影响 　　[摘要] 目的 探究急性期血糖水平对脑梗死患者近期预后的影响。方法 对2012年2月―2013年2月期间该院收治的87例急性期脑梗死患者进行空腹血糖监测，并按血糖监测结果，分为正常血糖组45例和高血糖组42例，分析高血糖水平对急性脑梗死近期预后的影响。 结果 高血糖组病灶梗死体积为（25.8±10.7）mm3，明显大于正常血糖组的（12.6±4.3）mm3；高血糖组患者入院不同时期的临床神经功能缺损NIHSS评分，均高于正常血糖组；入院1个月内，正常血糖组的住院病死率为2.22%，明显低于高血糖组的9.52%，组间比较差异有统计学意义（P0.05）。在高血糖组中，重度血糖水平组的病死率为15.00%，明显高于中度血糖水平的4.55%，不同血糖水平的病死率比较差异有统计学意义（P0.05）。 结论 高血糖可诱使急性期脑梗死患者病灶扩大，促使神经功能损伤加重，不利于病情恢复，并增加病死率，为此，严格的血糖控制可有效阻止急性脑梗死病情恶化，降低病死率，改善近期预后。 　　[关键词] 急性期；血糖；脑梗死；近期预后 　　[中图分类号] R743.3 [文献标识码] A [文章编号] 1674-0742（2014）08（b）-0062-02 　　[Abstract] Objective To study the effect of blood glucose level of patients with cerebral infarction during the acute stage on the short-term prognosis of the patients. Methods Fasting blood glucose monitoring was performed in 87 cases with acute cerebral infarction admitted in our hospital from February 2012 to February 2013. According to the result of blood glucose monitoring， the patients were divided into the normal blood glucose group of 45 cases and high blood glucose group of 42 cases. And the effect of hyperglycemia on the short-term prognosis of acute cerebral infarction was analyzed. Results The focal infarct volume of the high blood glucose group was （25.8±10.7） mm3， significantly larger than （12.6 ± 4.3） mm3 of the normal blood glucose group； the clinical neural function defect scores of NIHSS of the high blood glucose group in different periods of hospitalization were higher than those of the normal blood glucose group； within 1 month after the admission， the morality of the normal blood glucose group was 2.22%， significantly lower than 9.52% of the high blood glucose group， the difference between the groups was statistically significant， P0.05. In the high blood glucose group， the mortality of the subgroup with severe blood glucose level was 15.00%， significantly higher than 4.55% of the subgroup with moderate blood glucose level， the difference in mortality between patients with different blood glucose le