拉贝洛尔联合硫酸镁治疗妊娠高血压综合征的效果观察.docVIP

拉贝洛尔联合硫酸镁治疗妊娠高血压综合征的效果观察 　　[摘要] 目的 探讨拉贝洛尔联合硫酸镁治疗妊娠高血压综合征的临床效果。 方法 选取2011年7月～2013年6月本院收治的100例妊娠高血压综合征患者，将其随机分为观察组和对照组各50例。对照组采用硫酸镁进行治疗，观察组在对照组治疗的基础上加用拉贝洛尔进行治疗。比较两组治疗前后血压的改变、24 h尿蛋白量及分娩结局。 结果 治疗后两组收缩压及舒张压均明显下降，与治疗前比较，差异有统计学意义（P0.05）。 结论 拉贝洛尔治疗妊娠高血压综合征效果确切，可平稳维持血压，较好缓解蛋白尿，减少产后并发症。 　　[关键词] 拉贝洛尔；硫酸镁；妊娠高血压综合征 　　[中图分类号] R714.24+6 [文献标识码] A [文章编号] 1674-4721（2014）09（b）-0108-03 　　Effect observation of labetalol combined with magnesium sulfate in treatment of pregnancy induced hypertension syndrome 　　ZHU Ting1 ZHANG Tian-ming2 　　1.Department of Gynecology and Obstetrics，Maternal and Child Health Hospital of Xingcheng City in Liaoning Province，Xingcheng 125100，China；2.Class 5 of 2011 Grade，Medical College of Hubei Institute for Nationalities，Enshi 445000，China 　　[Abstract] Objective To study the clinical effect of labetalol combined with magnesium sulfate in the treatment of pregnancy induced hypertension syndrome. Methods 100 patients with pregnancy induced hypertension syndrome treated in our hospital from July 2011 to June 2013 were selected and randomly divided into the observation group and the control group，with 50 patients in each group.Magnesium sulfate was given to the control group，labetalol was added to the observation group on the basis of control group.The blood pressure changes，24-hour urine protein amount before and after treatment，delivery outcomes between the two groups were compared. Results The systolic pressure and diastolic pressure of both groups decreased significantly after treatment，compared with before treatment，the difference was significant （P0.05）. Conclusion In the treatment of pregnancy induced hypertension syndrome，labetalol shows accurate effects and can maintain blood pressure smoothly，relieve urine protein preferably and reduce postpartum complications. 　　[Key words] Labetalol；Magnesium sulfate；Pregnancy induced hypertension syndrome 　　妊娠高血压综合征是发生于妊娠20周以后的以血压升高、蛋白尿及水肿等为主要临床表现的孕产妇妊娠期特有的疾病[1]。流行病学资料显示，妊娠期孕妇约有9.4%会发生不同程度的高血压，严重者如不及时治