TCellDevelopment-TheUniversityofVermont-.pptVIP

Principles of ImmunologyT Cell-Mediated Immunity3/28/06 “Each of us needs to be the change we wish to see in the world” Ghandi Word/Terms List ADCC Effector cells GVH reaction Perforin T Cell-mediated Immunity Principal function-Response to intracellular pathogens and cells expressing foreign antigens Recirculation-Na?ve T cells circulate between the blood stream and the lymphatic system Antigen presentation-Na?ve T cell cells only respond to APCs Priming of T Cells Three types of effector T cells CD8 (TC) CD4 (TH1) CD4 (TH2) Each type Responds to different types of Ags