usp-32-氯化镁.docVIP

Magnesium Chloride MgCl2·6H2O 203.30 Magnesium chloride, hexahydrate Magnesium chloride hexahydrate [7791-18-6]. Anhydrous 95.21 [7786-30-3]. ? Magnesium Chloride contains not less than 98.0 percent and not more than 101.0 percent of MgCl2·6H2O. Packaging and storage— Preserve in tight containers. Labeling— Where Magnesium Chloride is intended for use in hemodialysis, it is so labeled. Identification— A solution (1 in 20) responds to the tests for Magnesium 191 and for Chloride 191. [note—When performing the test for Chloride, acidify the sample solution with diluted nitric acid prior to adding 6 N ammonium hydroxide.] pH 791: between 4.5 and 7.0, in a 1 in 20 solution in carbon dioxide-free water. Insoluble matter— Dissolve 20 g, accurately weighed, in 200 mL of water, heat to boiling, and digest in a covered beaker on a steam bath for 1 hour. Filter through a tared filtering crucible, wash thoroughly, dry at 115, and determine the weight of the residue: not more than 0.005% is found. Sulfate 221— A 10-g portion shows no more sulfate than corresponds to 0.50 mL of 0.020 N sulfuric acid (0.005%). Barium— Dissolve 1 g in 10 mL of water, and add 1 mL of 2 N sulfuric acid: no turbidity is produced within 2 hours. Limit of calcium— Dilute hydrochloric acid, Lanthanum solution, Standard preparations, and Blank solution— Proceed as directed in the test for Limit of calcium under Magnesium Carbonate. Test preparation— Transfer 10.0 g of Magnesium Chloride to a 200-mL volumetric flask, add water to dissolve it, add 4 mL of Lanthanum solution, dilute with water to volume, and mix. Procedure— Proceed as directed for Procedure in the test for Limit of calcium under Magnesium Carbonate. Determine the concentration, C, in μg per mL, of calcium in the Test preparation using the calibration graph. Calculate the content of calcium, in percentage, in the portion of Magnesium Chloride taken by the formula: 100(0.001CV/W) in which C is as defined above; the multiplier o