AntitumorigenicpotencyofPPZinxenograftmodel.pptVIP

Antitumorigenic potency of PPZ in xenograft model. Marie Yeo et al. Clin Cancer Res 2004;10:8687-8696 ?2004 by American Association for Cancer Research Antitumorigenic potency of PPZ in xenograft model. MKN-45 human gastric cancer cells were inoculated s.c. into the backs of athymic nude mice. PPZ 40 mg/kg was injected intratumorally IT 14 days after xenograft. Mice were sacrificed 22 days after tumor inoculation. Tumor volume was measured and represented A and B . The isolated tumors C were sectioned and processed for HE staining D, ×100 and ×400 magnification and TUNEL assay E, ×1