CVC操作和维护新探讨_培训课件.pptVIP

预防血管内导管相关感染的策略(七) 抗菌药物/消毒剂软膏 聚维酮碘软膏(皮维碘)敷于血液透析用导管穿刺点处，可预防导管相关感染 [1]。 莫匹罗星软膏（百多邦）敷于中心静脉导管穿刺点处，可降低CRBSI发生率[2]- [4] ，但是可诱导细菌对莫匹罗星发生耐药[5] [6] ，并且破坏聚氨基甲酸乙酯导管的完整性[7] [8] 。 [1] Levin A, Mason AJ, Jindal KK, Fong IW, Goldstein MB. Prevention of hemodialysis subclavian vein catheter infections by topical povidone-iodine. Kidney Int 1991;40:934--8. [2] Casewell MW. The nose: an underestimated source of Staphylococcus aureus causing wound infection. J Hosp Infect 1998;40(suppl):S3--S11. [3] Hill RL, Fisher AP, Ware RJ, Wilson S, Casewell MW. Mupirocin for the reduction of colonization of internal ju