tenhallmarksofcancer课程.pptVIP

Paper sharing:Hanahan D, Weinberg R. Hallmarks of Cancer: The Next Generation.Cell, 2011,144 5: 646-674. Dept. Medical Oncology, 1st Affiliated Hospital ****University Six hallmarks of cancer proposed in 2000 Emerging hallmarks Sustaining Proliferative Signaling The most fundamental trait of cancer cells involves their ability to sustain chronic proliferation Normal tissues ensuring a homeostasis by carefully control thing the production and release of growth-promoting signals Cancer cells, by deregulating these signals, become masters of their own destinies. The enabling signals are co