丁苯酞治疗进展性脑梗死50例疗效分析.docVIP

丁苯酞治疗进展性脑梗死50例疗效分析 宁世金 黄载文 广西钦州市第二人民医院 钦州 535000 【摘要】:目的 观察丁苯酞治疗进展性脑梗死的临床疗效。方法 将100例进展性脑梗死患者随机分为治疗组(50例)与对照组(50例)。对照组予血塞通注射液0.4g加入0.9%氯化钠注射液250ml静脉滴注，每日1次；胞二磷胆碱0.5g静滴，每日1次，阿司匹林100mg，每日1次口服。治疗组在对照组常规治疗基础上给予丁苯酞软胶囊0.2g，每日3次口服，疗程2周。治疗结束时观察两组治疗前后神经功能缺损评分(CSS) 与日常生活活动能力量表（Barthel Index，BI)评分情况。结果 治疗组治疗后神经功能缺损评分及 BI 评分明显改善，与对照组比较有统计学意义(P0.05)。治疗组临床总有效率为(88%)，明显高于对照组(70%)，差异有统计学意义(P0.05)。结论 丁苯酞治疗进展性脑梗死疗效肯定，能显著改善患者的预后。 【关键词】:丁苯酞；进展性脑梗死；临床疗效 Curative effect analysis of d-l3n-butylphthalide treating 50 patients with progressive cerebral infarc-tion (Ning Shi Jin, Huang Zai Wen,. Guangxi QinZhouShi second peoples hospital QinZhou,535000 China). 【Abstract】Objective To observe the clinical efficacy of d-l 3n-butylphthalide treating with progressive cerebral infarction Methods One hundred patients with progressive cere-bral infarction were randomized intoThe treatment group(50 cases) and The control group(50 cases). The control to the Blood flux injectionon 0.4g in 0.9% sodium chloride injection 250ml intravenous drip,one time per day, 100mg of aspirin, once-daily per os. Treatment group in the control group conventional treatment on the basis of butylphthalide soft for 0.2g per os three times a day, Treatment for two weeks Before and after treatment at the end of the observation of two groups of The clinical neurologic deficit scale (CSS) Results Treatment group after treatment of neural function defect score And BI score improved significantly ，Treatment group was statistically significant compared with controls (P0.05). Clinical treatment group total effective rate was( 88%) ,Significantly higher than the control group (70%), The difference was statistically significant (P 0.05),Conclusion Butyl phthalide curative effect on treatment of progressive cerebral infarction, Can significantly improve the prognosis of patients. 【Key words】 d-l 3n-butylphthalide; Progressive cerebral infarction;The clinical efficacy 进展性脑梗死(PCI)是指急性脑梗死（Cerebral