抗恶性肿瘤药34494课件.pptVIP

Worldwide overall annual cancer incidence Death rates for heart disease and cancer among people younger and older than age 85. 癌症特点 不受机体约束的增殖 与细胞增殖有关的基因被开启或激活； 与细胞分化有关的基因被关闭或抑制； 局部侵袭 (local invasiveness) 转移 (metastasis) 低分化 (less differentiated) 保留原组织一些特征 The Aim of Cancer Treatments Palliation——缓解症状，姑息治疗 Alleviation of symptoms Increased survival and improved quality of life Remission ——临床治愈 all macroscopic and microscopic features of the cancer disappear, though disease is known to persist Cure——治愈 all the cells of the clone must be destroyed 目前主要治疗手段 Six Established Therapeutic Modalities