先兆流产保胎成功后妊娠结局分析.docVIP

先兆流产保胎成功后妊娠结局分析 　　[摘 要] 目的：观察先兆流产保胎成功后妊娠结局，总结先兆流产保胎适应证。方法：选取我院2012年3月―2015年3月收治的327例孕产妇，将先兆流产保胎成功者纳入保胎组，将无先兆流产及其他高危因素者纳入对照组，比较2组产妇妊娠结局，随访新生儿生长发育情况。结果：2组产妇妊娠期及分娩期并发症发生情况、新生儿不良结局、新生儿0～3岁综合能力评分比较，差异均无统计学意义（P0.05）。结论：先兆流产保胎成功后不会对妊娠结局造成不良影响，但需注意保胎适应证选择，以保证妊娠的安全性及新生儿发育质量。 　　[关键词] 先兆流产；保胎；妊娠结局 　　中图分类号：R714.2 文献标识码：B 文章编号：2095-5200（2016）03-091-03DOI：10.11876/mimt201603034 　　[Abstract] Objective： To observe pregnancy outcome of successful prevention of miscarriage after threatened abortion， summarize indications for prevention of miscarriage after threatened abortion. Methods： 327 cases of pregnant women treated in our hospital from March 2012 to March 2015， the patients who was successfully prevented miscarriage after threatened abortion were include in fetus protection group， and no indication of threatened abortion and other risk factors were included in the control group， pregnancy outcomes of two groups were compared， and a follow-up was recorded for neonatal growth and development. Results： Complications of two groups during pregnancy and childbirth， the adverse neonatal outcomes， comprehensive ability score of 0-3 years old newborn were compared， the difference was not statistically significant （P0.05）. Conclusions： Successful prevention of miscarriage after threatened abortion has no adverse effects on pregnancy outcomes， but miscarriage indications should be paid attention to ensure the safety of pregnancy and quality of neonatal development. 　　[Key words] threatened abortion； fetus protection； pregnancy outcomes 　　先兆流产约占全部妊娠的10%～15%，以阴道少量流血、阵发性下腹部疼痛为主要临床表现，此时产妇宫口未开、胎膜完整且无妊娠物排出，经积极保胎治疗后可正常妊娠[1]。但先兆流产往往病因复杂，对因治疗困难，同时，过往有报道指出先兆流产即使保胎成功，胎儿亦有着较高的先天畸形发生率，且产妇大出血风险较高[2]。但有学者认为，近年来随着先兆流产诊疗技术的提高，保胎成功后不会对妊娠结局造成明显影响[3]。故目前先兆流产保胎成功后是否继续妊娠、是否会对妊娠结局造成影响值得探讨。为明确先兆流产保胎成功后妊娠结局，本研究选取我院收治的327例孕产妇进行了前瞻性研究，现将研究方法与结果报道如下。 　　1 资料与方法 　　1.1 临床资料 　　选取我院2012年3月―2015年3月收治的327例单胎妊娠且成功分娩产妇。将先兆流产保胎成功且无其他高危因素者纳入保胎组（158例），将无先兆流产及其他高危因素者纳入对照组（169例）。2组孕产妇一般临床资料比较如表1所示，其年龄、孕周、孕次、产次、文化程度比较