低热量肠内营养联合肠外营养对消化道肿瘤术后的临床疗效分析.docVIP

低热量肠内营养联合肠外营养对消化道肿瘤术后的临床疗效分析 　　[摘要] 目的 考察低热量肠内营养联合肠外营养对消化道肿瘤术后的临床辅助疗效。 方法 回顾浙江省宁波市第二医院2008年3月～2012年7月收治的消化道肿瘤患者的临床诊治资料，筛选150名消化道肿瘤患者为研究对象。对照组和实验组分别为75名，对照组给予单独的肠外营养治疗，实验组给予低热量肠内营养和肠外营养的联合治疗。对两组患者治疗过程中的营养状况、免疫状况和并发症发生率等方面进行对比评价，考察两种治疗方案的疗效差异。 结果 在营养状况方面，实验组患者术后1、7、10 d的白蛋白、转铁蛋白等水平均高于对照组，且差异均有统计学意义（P 0.05）。在免疫状况方面，实验组患者术后1、7、10 d的IgA、IgM等免疫指标的水平均高于对照组，且差异有统计学意义（P 0.05）。此外，在住院时间、肠道功能恢复时间、体重变化以及合并症发生率等方面，实验组也优于对照组[（8.00±1.67）d比（12.00±1.83）d，（53.2±5.4）h比（74.1±5.9）h，（2.81±0.32）%比（3.12±0.84）%，9.33%比34.67%]，且差异有统计学意义（P 0.01或P 0.05）。 结论 低热量肠内营养联合肠外营养能够有效加速消化道肿瘤患者术后的康复进程，降低合并症的复发率，具有较大的临床推广意义。 　　[关键词] 肠内营养；肠外营养；消化道肿瘤；营养支持 　　[中图分类号] R576 [文献标识码] A [文章编号] 1673-7210（2013）11（a）-0037-04 　　Clinical effect analysis of gastrointestinal tumors after surgery by hypocaloric enteral nutrition combining with parenteral nutrition 　　YING Jingjing1 DAI Ning2 　　1.The Second Hospital of Ningbo， Zhejiang Province， Ningbo 315010， China； 2.Sir Run Run Shaw Hospital Affiliated to Medical School of Zhejiang University， Zhejiang Province， Hangzhou 310016， China 　　[Abstract] Objective To observe the clinical auxiliary effects of gastrointestinal tumors after surgery by hypocaloric enteral nutrition combining with parenteral nutrition. Methods Clinical diagnosis and treatment data of patients with gastrointestinal tumors admitted into the Second Hospital of Ningbo from March 2008 to July 2012 were reviewed， and 150 patients were selected as research objects. They were randomly divided into control group and experiment group. In the control group， only parenteral nutrition therapy was provided， while in the experiment group， the combination therapy of hypoclaoric enteral nutrition and parenteral nutrition was applied. The nutritional status， immune state， and incidence of complications in the process of treatment in both groups were comparatively analyzed in order to observe the effect differences between the two therapeutic regimens. Results In the aspect of nutritional status， the leve