肠梗阻导管联合生长抑素治疗重症急性胰腺炎.docVIP

肠梗阻导管联合生长抑素治疗重症急性胰腺炎 　　DOI：10.3760/cma.j.issn.1671-0282.2013.11.017 　　作者单位：518103 深圳，深圳市福永人民医院急诊科（阳生光、苏科），普外科（朱燕辉），检验科（向华国）；深圳市光明新区人民医院ICU（陈锋） 　　【摘要】目的 分析肠梗阻导管（IT）联合生长抑素（SS）对重症急性胰腺炎（SAP）患者的作用效果。方法 在常规处理的基础上，75例SAP患者按治疗方法不同分为A组（IT联合SS组）、B组（普通鼻胃管加SS组）和C组（IT组）。分别观察三组患者的治疗效果，临床指标的转归，胃肠减压引流量的动态变化及预后。结果 治疗效果：A组有效率为100%、B组84%、C组80%。A、B组比较：χ2=8.26，差异具有统计学意义（P0.01）；B、C组比较：χ2=0.38，差异无统计学意义（P0.05）。A组各项临床指标比B、C组恢复快，差异具有统计学意义（P0.05）。减压引流量：A与B、B与C、C与A组间比较， t 值分别是2.14、3.83、2.23，差异均具有统计学意义（P0.05）。结论 IT联合SS应用可显著改善SAP患者的病情，减少中转手术率，缩短留医时间，降低病死率，改善预后，值得临床中推广。 　　【关键词】 重症急性胰腺炎；导管；生长抑素；减压；治疗效果 　　Ileus decompression tube combined with somatostatin for the treatment of severe acute pancreatitis YANG Sheng-guang，SU Ke，ZHU Yan-hui，CHEN Feng， XIANG Hua-guo. Emergency Department， Fu Yong People’s Hospital in Shenzhen， Shenzhen 518103， China. 　　【Abstract】Objective To analyze the effects of Ileus tube （IT） along with somatostatin（SS） used for treatment of patients with severe acute pancreatitis （SAP）.Methods Under conventional treatment， 75 patients with SAP were divided into three groups as per different additional treatments， namely group A （IT and SS）， group B （nasogastric decompression tube and SS）， and group C （IT alone）， and the therapeutic efficacies of those treatments were evaluated in respects of improvement of physical signs and symptems， dynamic changes in decompression drainage and prognosis.Results Therapeutic efficacy was 100% in group A， 84% in group B and 80% in group C. The difference between group A and B was χ2=8.26 （P0.01）； group B vs. C was χ2=0.38 （P0.05）. The physical signs and symptoms in group A were improved more rapid than those in group B and C （P0.05）. In comparison of decompression drainage， the t value of group A vs. group B was 2.14， group B vs. group C was 3.83， and group A vs. group C was 2.23 （P0.05）. Conclusions Application of IT combined with SS can significantly improve the condition of patients with SAP， thereby reducing the operation rate， shorte