泮托拉唑联合生长抑素治疗急性上消化道出血效果探究.docVIP

泮托拉唑联合生长抑素治疗急性上消化道出血效果探究 　　【摘要】目的：探讨生长抑素与泮托拉唑联合治疗急性上消化道出血的临床效果。方法：抽取84例急性上消化道出血患者，将其分为对照组和治疗组各42例。对照组采用泮托拉唑进行治疗；治疗组采用生长抑素联合泮托拉唑进行治疗。结果：治疗组患者急性上消化道出血症状治疗效果明显优于对照组（P0.05）；患者成功止血时间和住院接受治疗时间明显短于对照组（P0.05）；治疗期间不良反应和治疗后复发人数明显少于对照组（P0.05）。结论：生长抑素与泮托拉唑联合治疗急性上消化道出血临床效果非常明显。 　　【关键词】生长抑素；泮托拉唑；急性上消化道出血 　　 　　The Clinical Effects of Pantoprazole Combined with Somatostatin in the Treatment of Acute Upper Gastrointestinal Hemorrhage/GAO Yong-liang，XIA Ji-qiang.//Medical Innocation of China，2013，10（20）：025-026 　　【Abstract】Objective：To study the clinical effects of pantoprazole combined with somatostatin in the treatment of acute upper gastrointestinal hemorrhage. Method： 84 acute upper gastrointestinal hemorrhage patients were divided into control group and treatment group， 42 patients in each group. The patients in thecontrol group were treated with pantoprazole， and the patients in the treatment group were treated with pantoprazole combined with somatostatin.Result：The clinical effects of the treatment group were significantly better than that of the control group；the time of successful hemostasis and hospitalization of the treatment group were significantly less than that of the control group.Further more，the combined treatment group had less incidence of adverse reactions and recurrence rate.Conclusion：The combination of somatostatin and pantoprazole has significant clinical effects in the treatment of acute upper gastrointestinal hemorrhage. 　　【Key words】Somatostatin；Pantoprazole；Acute upper gastrointestinal hemorrhage 　　First-author’s address：Liaoyuan Central Hospital， Liaoyuan 136200， China 　　doi：10.3969/j.issn.1674-4985.2013.20.012 　　上消化道出血是临床上常见的一种内科急症，该病病情普遍比较凶险，通常情况下会继发出现失血性休克、多器官衰竭等并发症，病死率可以高达20%， 目前临床对上消化道出血患者进行治疗的首选方法仍然为药物治疗，包括血管加压素、垂体后叶素等，但实际治疗有效率并不高，且产生的毒副作用较大，特别是对于一些合并有冠心病、心肌梗死的患者还不能够应用这些药物进行治疗[1-2]。本研究对生长抑素与泮托拉唑联合治疗急性上消化道出血的临床效果进行研究。现将研究过程和结果汇报如下。 　　1资料与方法 　　1.1一般资料抽取2008年3月-2012年3月84例急性上消化道出血患者，将其分为对照组和治疗组各42例。对照组患者中男27例，女15例；年龄24~76岁，平均41.9岁；治疗组患者中