注射用胸腺五肽辅助治疗带状疱疹的疗效观察.docVIP

注射用胸腺五肽辅助治疗带状疱疹的疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.16.47 　　摘 要 目的：探讨注射用胸腺五肽治疗带状疱疹患者的临床疗效。方法：2013年4-10月收治带状疱疹患者68例，随机分为对照组30例和治疗组38例，对照组给予更昔洛韦静滴5mg/（kg?日），连用10天，外用5%硫磺炉甘石洗剂，并发感染者用克林霉素抗感染治疗。治疗组在对照组基础上加用注射用胸腺五肽1mg，2次/日，连用10天，比较两组的临床疗效。结果：治疗组在止痘、皮损愈合及疼痛缓解时间上均优于对照组，差异有统计学意义（P0.05）。结论：注射用胸腺五肽治疗带状疱疹具有较好的临床效果。 　　关键词 注射用胸腺五肽 带状疱疹 疗效观察 　　Curative effect observation of thymopentin？for injection in the treatment of herpes zoster 　　Zheng Liyun 　　Harbin Pharmaceutical Group Biological Engineering Limited Company（Haerbin City，Heilongjiang），150001 　　Abstract Objective：To explore the clinical effect of thymopentin？for injection in the treatment of herpes zoster.Methods：68 cases with herpes zoster were selected from April to October 2013.They were randomly divided into the control group with 30 cases and the treatment group with 38 cases.The control group were treated with ganciclovir intravenous drip 5mg/（kg?day），for 10 days，5% topical sulfur calamine lotion，concurrent infection patietns were treated with clindamycin anti infection treatment.The treatment group were treated with 1mg thymopentin for injection on the basis of conventional treatment，2 times/day，for 10 days.The clinical curative effects of the two groups were compared.Results：The stopping blain，remission time of pain and lesion healing agent of the treatment group were better than that of the control group.There was significant differences（P0.05）.Conclusion：The clinical effect of thymopentin？for injection in the treatment of herpes zoster is better than the conventional treatment. 　　Key words Thymopentin？for injection；Herpes zoster；Curative effect observation 　　带状疱疹是一种急性感染性皮肤病，通常由水痘-带状疱疹病毒引起，由于该病毒具有亲神经性，在患者感染后可使受侵犯神经和皮肤产生严重的炎症[1]。现代医学研究表明，带状疱疹的发生与患病人群机体自身的免疫功能有密切的关系。我院采用注射用胸腺五肽辅助治疗带状疱疹，取得较好疗效。 　　资料与方法 　　本组患者68例，男33例，女35例，年龄27～61岁（严重肝肾功能不全患者不作为入选条件）。患者患病部位均处于周围神经分布部位，有疱疹和剧烈的神经疼痛，其中颅神经受累14例，颈神经受累11例，其余患者均为胸神经及腰神经受累。将所有患者随机分为对照组30例（病程3～11天）和治疗组38例（病程4～12天）。 　　治疗方法：对照组给予更昔洛韦静滴5mg/（kg?日），连用10天，外用5%硫磺炉甘石