脱落细胞FNAC课件.pptVIP

细针吸取细胞学检查(fine needle aspiration cytology) 使用细针穿刺病灶吸取出少量细胞成分作涂片来观察病灶部位肿瘤或非肿瘤性细胞的形态，从而作出诊断。 细针吸取活检( fine needle aspiration biopsy ) 细针细胞病理(fine needle aspiration cytopathology) 细针吸取细胞学检查(fine needle aspiration cytology) Advantages The advantages of FNA biopsy can be summed up in the acronym SAFE. It is Simple, Accurate, Fast, and Economic, as well as safe. 细针吸取细胞学检查(fine needle aspiration cytology) Deep-Seated Organ Aspirations FNA biopsy of deep-seated organs, such as lung, liver, pancreas, kidney, or adrenal, is in many ways similar to, but in some ways different from, FNA biopsy of superficial targets. Ultrasound, Computered Tomography Guiding the Needle 细针吸取细胞学检查(fine needle aspiration cytology) Disadvantages 样本采集 涂片制作 细胞学诊断 淋巴结针吸细胞学检查 淋巴结针吸细胞学检查：操作简便，快速安全，对于明确淋巴结良恶性病变的性质、快速诊断淋巴结疾病，包括各类反应性增生和淋巴结转移癌及恶性淋巴瘤，具有临床实用价值。 正常淋巴结细胞学 　正常淋巴结穿刺涂片标本淋巴细胞占95%以上，以成熟小淋巴细胞为主，其余5%为幼淋巴细胞、原淋巴细胞、网状细胞和浆细胞等。 正常淋巴结细胞学 Lymphocytes. Benign, reactive pattern, with predominance of small, mature lymphocytes, a range of maturation of immature lymphocytes, and a fully differentiated plasma cell. (Diff-Quik) 正常淋巴结细胞学 Lymphocytes. The benign pattern showing a range of maturation of lymphocytes, including mature plasma cells. (Pap) 正常淋巴结细胞学 Tingible body macrophages. Specialized histiocyte that engulfs dead (necrobiotic) cells. Associated with germinal center formation and benign lymphadenopathy, but can be seen in any high-grade lymphoma. (Pap) 淋巴结良性病变针吸细胞检查 慢性淋巴结炎： 本病常见，多由局部慢性感染引起，好发于颈部、颌下和腹股沟等处； 涂片内有大量小淋巴细胞，夹有少量转化的淋巴细胞及组织细胞，有吞噬现象； 慢性淋巴结炎 慢性淋巴结炎 Chronic lymphadenitis  Chronic lymphadenitis is probably the most common diagnosis in aspiration of enlarged lymph nodes. A cellular smear with numerous immature, or follicular center cells, but an overall predominance of small, mature lymphocytes. Tingible body macrophages and lymphohistio-cytic aggregates also present. Mitotic figures may be seen. (Diff-Quik). 慢性淋巴结炎 Chronic lymphadenitis Follicular hyperplasia, with lar