大学本科医学毕业论文—肥胖症的多学科综合治疗模式试题.doc

肥胖症的多学科综合治疗模式 摘要：肥胖症在我国及世界多国迅速增长，威胁到人类健康，引起了代谢性疾病的增长和疾病谱改变；其伴发疾病、死亡率及引发相关的社会经济问题亟待世界性关注。近年来，对于肥胖的治疗也从单纯饮食、运动和药物治疗，转向了多学科综合治疗模式。对于保守治疗效果欠佳的重度肥胖患者（体重指数40kg/m2）或体重指数介于35～40kg/m2且合并肥胖相关合并症，如严重糖尿病、肥胖相关心肌病变、严重睡眠呼吸暂停、不育、影响日常生活的骨关节炎等疾病患者，选择微创腹腔镜减肥手术治疗（如可调节胃束带术等）可获得长期稳定的减重治疗效果，特别是对合并症的明显治愈或预防改善作用，并最终降低死亡率。多学科综合治疗模式已在恶性肿瘤及肥胖症等多种疾病的治疗中被大多数国家和医院所采用。现代多学科优势，对于提高疾病诊疗效果和医疗服务水平，共同探讨解决边缘学科难题，促进相关学科学术水平提高，将发挥越来越重要的作用。 关键词：肥胖症；多学科；综合治疗模式 中图分类号：R459.3；R656 文献标志码：A 文章编号：1000-503X（2010）01-0001-03DOI：10.3881/j.issn.1000-503X.2010.01.001 Integrated Multidisciplinary Treatment Modalities for ObesityYU Jian-chunDepartment of General Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, ChinaTel/Fax：010E-mail：yu-jch@163.comABSTRACT:The rapid increase of obesity nationwide and worldwide has threatened human health and caused the increase of metabolic diseases and the changes of disease spectrum. Its co-morbidities, mortality, and relevant socio-economic issues have became global concerns. Integrated multidisciplinary treatment modalities have emerged in recent years. For severely obese patients ［body mass index (BMI）40 kg/m2］ or obese patients (BMI 35 - 40 kg/m2) with co-morbidities such as severe diabetes, obesity-associated cardiac lesions, severe sleep apnea, infertility, and osteoarthritis that affect the daily life, minimally invasive laparoscopic bariatric surgery (such as Lap Banding) can achieve satisfactory results by reducing body weight in long term, treating or preventing the co-morbidities, and ultimately decreasing mortality. Multidisciplinary treatment modalities for tumors, obesity, and other diseases have been widely adopted. This strategy may play increasingly important roles in improving the treatment effectiveness, upgrading healthcare services, and addressing interdisciplinary problems.Key words：obesity；multidisplinary team; integrated treatment modalitiesActa Acad Med Sin，2010，32（1）：1-3 基金项目：卫生部内分泌重点实验室资助课题Supported by the Endocrine Major Laboratory Finan