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AIDS 1. Concept: Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV) It is transmitted through direct contact of a mucous membrane or the bloodstream with a bodily fluid containing HIV, such as blood, semen, vaginal fluid, preseminal fluid, and breast milk. 2.History: Genetic research indicates that HIV originated in west-central Africa during the late nineteenth or early twentieth century. AIDS was first recognized by the U.S. Centers for Disease Control and Prevention in 1981 and its cause, HIV, identified in the early 1980s. AIDS is now a pandemic. 3.CAUSE: a)Sexual transmission The majority of HIV infections are acquired through unprotected sexual relations between partners, one of whom has HIV. The primary mode of HIV infection worldwide is through sexual contact between members of the opposite sex. b)Exposure to blood-borne pathogens This transmission route is particularly relevant to intravenous drug users, hemophiliacs and recipients of blood transfusions and blood products. Sharing and reusing syringes contaminated with HIV-infected blood represents a major risk for infection with HIV. c) Perinatal transmission The transmission of the virus from the mother to the child can occur in utero during the last weeks of pregnancy and at childbirth. 4.Symptoms: The symptoms of AIDS are primarily the result of conditions that do not normally develop in individuals with healthy immune systems. Opportunistic infections are common in people with AIDS. These infections affect nearly every organ system. People with AIDS also have an increased risk of developing various cancers such as Kaposis sarcoma, cervical cancer and cancers of the immune system known as lymphomas. Additionally, people with AIDS often have systemic symptoms of infection like fevers, sweats (particularly at night), swollen glands, chills, weakness, and weight loss. 5.
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